Zoonotic infections in pediatric patients with acute leukemia

Pediatr Blood Cancer. 2013 Dec;60(12):E160-2. doi: 10.1002/pbc.24596. Epub 2013 Aug 19.

Abstract

Few studies have described the impact of zoonotic diseases in children with leukemia. This study aimed to describe the frequency of and associated demographic factors for zoonotic diseases in pediatric acute leukemia patients. Descriptive and comparative statistics relative to age, sex, and patient region were performed on an assembled 11-year retrospective cohort of acute leukemia patients. Of 10,197 patients, 88 patients (0.86%) were found to have a zoonotic infection. Gastrointestinal diseases were the most commonly (86.4%) identified zoonotic illnesses. Although rare, zoonotic diseases do occur in children with leukemia and frequency varies by age, region, and gender.

Keywords: acute pediatric leukemia; maintenance chemotherapy; opportunistic infections; zoonotic diseases.

MeSH terms

  • Acute Disease
  • Adolescent
  • Animals
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Leukemia / complications*
  • Male
  • Prevalence
  • Young Adult
  • Zoonoses / complications*
  • Zoonoses / epidemiology*