Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen

Cancer Genet Cytogenet. 1990 Oct 1;49(1):133-6. doi: 10.1016/0165-4608(90)90174-9.

Abstract

A case of early B t(4;11)(q21;q23) acute lymphoblastic leukemia (ALL) with low white blood cell (WBC) count, without splenomegaly, short survival time, in a patient previously exposed to benzol is presented. We discuss the relationship between the t(4;11)(q21;q23) and the exposure to a carcinogen.

Publication types

  • Case Reports

MeSH terms

  • Benzene / toxicity*
  • Chromosomes, Human, Pair 11*
  • Chromosomes, Human, Pair 4*
  • Female
  • Genetic Markers
  • Humans
  • Karyotyping
  • Middle Aged
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / genetics
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / chemically induced*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Translocation, Genetic*

Substances

  • Genetic Markers
  • Benzene