Yield of screening for TB and HIV among children failing to thrive in Botswana

J Trop Pediatr. 2014 Feb;60(1):27-32. doi: 10.1093/tropej/fmt072. Epub 2013 Aug 27.

Abstract

Background: Failure to thrive (FTT) is a sign of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. We assessed TB and HIV prevalence in children with FTT at one clinic in Botswana.

Methods: In July 2010, we screened all children attending a 'Well Child' clinic for FTT. Children with FTT were referred to a paediatrician who: (i) assessed causes of FTT, (ii) evaluated for HIV and TB and (iii) reviewed the patient chart for evaluations for TB and HIV.

Results: Of 919 children screened, 176 (19%) had FTT. One hundred eighteen (67%) children saw a paediatrician, and of these, 95 (81%) completed the TB evaluation. TB was newly diagnosed in 6 of 95 (6%). At review, HIV status was known in 23 of 118 (19%). Ninety-five had an unknown HIV status. Forty-five (47%) tested for HIV; all tested HIV-negative.

Conclusion: TB and HIV screening among children with FTT diagnosed TB in 6% of cases completing an evaluation, but no new HIV infections.

Keywords: HIV; children; failure to thrive; tuberculosis.

MeSH terms

  • Botswana / epidemiology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Failure to Thrive / diagnosis
  • Failure to Thrive / epidemiology
  • Failure to Thrive / etiology*
  • Female
  • Follow-Up Studies
  • HIV Infections / complications
  • HIV Infections / diagnosis*
  • HIV Infections / epidemiology*
  • Humans
  • Infant
  • Male
  • Mass Screening / methods*
  • Outcome and Process Assessment, Health Care
  • Outpatient Clinics, Hospital
  • Prevalence
  • Socioeconomic Factors
  • Tuberculosis / complications
  • Tuberculosis / diagnosis*
  • Tuberculosis / epidemiology*
  • Urban Population / statistics & numerical data