Tissue transglutaminase generates deamidated epitopes on gluten, increasing reactivity with hydrolyzed wheat protein-sensitized IgE

J Allergy Clin Immunol. 2013 Dec;132(6):1436-8. doi: 10.1016/j.jaci.2013.07.017. Epub 2013 Aug 30.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Allergens / immunology
  • Cells, Cultured
  • Child
  • Child, Preschool
  • Epitopes, B-Lymphocyte / immunology
  • Female
  • GTP-Binding Proteins
  • Glutens / chemistry
  • Glutens / immunology*
  • Humans
  • Hydrolysis
  • Immunoglobulin E / metabolism
  • Infant
  • Male
  • Middle Aged
  • Protein Glutamine gamma Glutamyltransferase 2
  • Serologic Tests / methods
  • Transglutaminases / immunology*
  • Triticum
  • Wheat Hypersensitivity / diagnosis
  • Wheat Hypersensitivity / immunology*
  • Young Adult

Substances

  • Allergens
  • Epitopes, B-Lymphocyte
  • Immunoglobulin E
  • Glutens
  • Protein Glutamine gamma Glutamyltransferase 2
  • Transglutaminases
  • GTP-Binding Proteins