Assessment of a new Bacteroidales marker targeting North American beaver (Castor canadensis) fecal pollution by real-time PCR

J Microbiol Methods. 2013 Nov;95(2):201-6. doi: 10.1016/j.mimet.2013.08.016. Epub 2013 Aug 31.

Abstract

In many settings wildlife can be a significant source of fecal pathogen input into surface water. The North American beaver (Castor canadensis) is a zoonotic reservoir for several human pathogens including Cryptosporidium spp. and Giardia spp. In order to specifically detect fecal pollution by beavers, we have developed and validated a beaver-specific Bacteroidales marker, designated Beapol01, based on the 16S rRNA gene. The marker is suitable for quantifying pollution using real-time PCR. The specificity and sensitivity of the marker was excellent, Beaver signal was detected in water of a mixed-activity watershed harbouring this rodent. Overall, Beapol01 will be useful for a better understanding of fecal source inputs in drainage basins inhabited by the beaver.

Keywords: Beaver-specific marker; Microbial source tracking; Real-time PCR; Waterborne pathogens.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacteroidetes / genetics
  • Bacteroidetes / isolation & purification*
  • Colony Count, Microbial
  • DNA, Bacterial / genetics
  • Environmental Monitoring / methods*
  • Escherichia coli / isolation & purification
  • Feces / microbiology*
  • Ontario
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Real-Time Polymerase Chain Reaction / methods*
  • Rodentia / microbiology*
  • Sensitivity and Specificity
  • Sequence Analysis, DNA
  • Water Microbiology
  • Water Pollutants / analysis

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S
  • Water Pollutants