[Thrombocytopenia induced by heparin and cardiac surgery with extracorporeal circulation]

Ann Fr Anesth Reanim. 1990;9(4):393-5. doi: 10.1016/s0750-7658(05)80255-2.
[Article in French]

Abstract

A case of mitral and aortic valvular replacement combined with double coronary artery bypass grafting is reported in a 64-year-old woman who presented with a history of heparin-induced thrombocytopenia. The use of a conventional dose of heparin did not induce the formation of a plasma platelet-aggregation factor. The necessity of postoperative anticoagulation was ensured by the prescription of antivitamin K, started on the morning of the operative day.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Blood Coagulation Factors / isolation & purification
  • Cardiac Surgical Procedures*
  • Extracorporeal Circulation
  • Female
  • Heparin / adverse effects*
  • Heparin / therapeutic use
  • Humans
  • Middle Aged
  • Platelet Activating Factor*
  • Platelet Aggregation / drug effects
  • Postoperative Period
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / immunology
  • Vitamin K / antagonists & inhibitors

Substances

  • Blood Coagulation Factors
  • Platelet Activating Factor
  • Vitamin K
  • Heparin