Acute HIV-1 seroconversion with an unusual plasma biomarker profile

Clin Vaccine Immunol. 2013 Nov;20(11):1774-7. doi: 10.1128/CVI.00366-13. Epub 2013 Sep 4.

Abstract

An unusual case of acute primary HIV-1 infection in a man with a high plasma viral load, a 51-fold increase in C-reactive protein, and antibodies against only gp160 is described. Numerous serum cytokine concentrations were elevated during HIV-1 seroconversion.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Antibodies, Viral / blood*
  • Biomarkers / blood*
  • C-Reactive Protein / analysis
  • Cytokines / blood
  • HIV Infections / diagnosis*
  • HIV Infections / immunology
  • HIV Infections / virology
  • HIV-1 / isolation & purification*
  • Humans
  • Male
  • Middle Aged
  • Plasma / chemistry
  • Viral Load*

Substances

  • Antibodies, Viral
  • Biomarkers
  • Cytokines
  • C-Reactive Protein