On the heterogeneous composition of bacterial polyhydroxyalkanoate terpolymers

Bioresour Technol. 2013 Nov:147:434-441. doi: 10.1016/j.biortech.2013.08.009. Epub 2013 Aug 11.

Abstract

Poly(3-hydroxybutyrate-4-hydroxybutyrate-3-hydroxyvalerate) (P(3HB-4HB-3HV)) terpolymers of low 3-hydroxyvalerate (3HV) content (1.7-6.4%) with 4-hydroxybutyrate (4HB) molar fractions from 1.8% to 35.6% were produced by fed-batch cultivation of Cupriavidus necator DSM545. Waste glycerol, γ-butyrolactone and propionic acid were used as main carbon source, 4HB and 3HV precursors, respectively. Uniaxial tensile tests were performed on the corresponding biopolymers. The Young's modulus and tensile strength of P(3HB-4HB-3HV) decreased, whereas the elongation at break increased with the 4HB molar%, following the general trend described for poly(3-hydroxybutyrate-4-hydroxybutyrate) (P(3HB-4HB)) but with pronounced lower elasticity. Differential scanning calorimetry results indicate that the temperature of crystallization and enthalpy of melting decreased as the 4HB% increased. No crystallization was observed in terpolymers containing more than 30% of heteromonomers (4HB and 3HV) even though multiple melting events were detected. Terpolymer fractions of different composition were obtained by solvent-fractionation of the original bacterial terpolymers.

Keywords: Mechanical properties; PHA fractionation; Poly(3-hydroxybutyrate-4-hydroxybutyrate-3-hydroxyvalerate); Thermal properties; Waste glycerol.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopolymers / metabolism*
  • Calorimetry, Differential Scanning
  • Chromatography, Gel
  • Crystallization
  • Cupriavidus necator / metabolism*
  • Magnetic Resonance Spectroscopy
  • Polyhydroxyalkanoates / metabolism*
  • Tensile Strength
  • Thermodynamics

Substances

  • Biopolymers
  • Polyhydroxyalkanoates