Phase I trial of PALA, methotrexate, fluorouracil, leucovorin, and uridine rescue in patients with advanced cancer. The use of uridine to decrease fluorouracil toxicity

Cancer Invest. 1990;8(2):263-4. doi: 10.3109/07357909009017578.
No abstract available

MeSH terms

  • Adult
  • Aged
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Aspartic Acid / administration & dosage
  • Aspartic Acid / analogs & derivatives
  • Drug Evaluation
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects
  • Humans
  • Leucovorin / administration & dosage
  • Male
  • Methotrexate / administration & dosage
  • Middle Aged
  • Neoplasms / drug therapy*
  • Phosphonoacetic Acid / administration & dosage
  • Phosphonoacetic Acid / analogs & derivatives
  • Uridine / administration & dosage
  • Uridine / pharmacology

Substances

  • Antimetabolites, Antineoplastic
  • Aspartic Acid
  • sparfosic acid
  • Phosphonoacetic Acid
  • Leucovorin
  • Fluorouracil
  • Uridine
  • Methotrexate