Renal lesions in autoimmune pancreatitis: diffusion weighted magnetic resonance imaging for assessing response to corticosteroid therapy

JOP. 2013 Sep 10;14(5):506-9. doi: 10.6092/1590-8577/1400.

Abstract

Context: Autoimmune pancreatitis is a rare disorder characterized by the systemic deposition of IgG4 plasma cells. Extrapancreatic manifestations of autoimmune pancreatitis depend on the site of plasma cell deposition. The most common extrapancreatic site of involvement is the bile duct followed by the retroperitoneum and kidneys.

Case report: We report a case of a patient with autoimmune pancreatitis and renal lesions who underwent MRI prior to and after corticosteroid therapy.

Conclusion: We emphasize the role of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) findings on MRI in evaluating the response to steroid therapy.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Diseases / blood
  • Autoimmune Diseases / diagnosis*
  • Autoimmune Diseases / drug therapy
  • Diffusion Magnetic Resonance Imaging / methods
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulin G / blood
  • Kidney / drug effects
  • Kidney / pathology*
  • Male
  • Middle Aged
  • Pancreatitis / blood
  • Pancreatitis / diagnosis*
  • Pancreatitis / drug therapy
  • Prednisone / therapeutic use
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Immunoglobulin G
  • Prednisone