Substrate hydrolysis triggered formation of fluorescent gold nanoclusters--a new platform for the sensing of enzyme activity

Chem Commun (Camb). 2013 Oct 28;49(84):9821-3. doi: 10.1039/c3cc45494k.

Abstract

Substrate hydrolysis was utilized to trigger a "top-down" etching process for the generation of fluorescent gold nanoclusters, and the changes in emission intensity of the assay solution provide a facile way for the sensing of enzyme activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Enzyme Activation
  • Enzymes / chemistry
  • Enzymes / metabolism*
  • Fluorescence*
  • Gold / chemistry
  • Gold / metabolism*
  • Hydrolysis
  • Metal Nanoparticles / chemistry*
  • Particle Size
  • Surface Properties

Substances

  • Enzymes
  • Gold