Difluoro(sulfinato)methylation of N-sulfinyl imines facilitated by 2-pyridyl sulfone: stereoselective synthesis of difluorinated β-amino sulfonic acids and peptidosulfonamides

Angew Chem Int Ed Engl. 2013 Oct 4;52(41):10835-9. doi: 10.1002/anie.201304395. Epub 2013 Aug 22.

Authors

G K Surya Prakash¹, Chuanfa Ni, Fang Wang, Zhe Zhang, Ralf Haiges, George A Olah

Affiliation

¹ Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA-90089-1661 (USA). [email protected].

PMID: 24038893
DOI: 10.1002/anie.201304395

No abstract available

Keywords: NMR spectroscopy; fluorine; peptidomimetics; sulfonamides; synthetic methods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Halogenation
Imines / chemistry*
Methylation
Peptidomimetics / chemical synthesis*
Peptidomimetics / chemistry
Stereoisomerism
Sulfonamides / chemical synthesis*
Sulfonamides / chemistry
Sulfones / chemistry*
Sulfonic Acids / chemical synthesis*
Sulfonic Acids / chemistry

Substances

Imines
Peptidomimetics
Sulfonamides
Sulfones
Sulfonic Acids
sulfamic acid