A 52-year-old-male patient with metastatic non-small-cell lung cancer and recurrent venous thromboembolism in unusual sites despite anticoagulation

BMJ Case Rep. 2013 Sep 17:2013:bcr2013200502. doi: 10.1136/bcr-2013-200502.

Abstract

The link between cancer and venous thromboembolism is well known, with an annual incidence rate of venous thromboembolism between 0.5% and 20% depending on the primary site and background risk factors. Current guidelines suggest treatment with low-molecular-weight heparin over oral vitamin K antagonists. However, data regarding the management of recurrent venous thromboembolism when the patient is under treatment with anticoagulants are sparse. In this article we present a patient with multiple thromboembolic events in unusual sites despite anticoagulant treatment and we discuss the management options.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary*
  • Carcinoma, Non-Small-Cell Lung / secondary*
  • Fatal Outcome
  • Fibrinolytic Agents / therapeutic use*
  • Heparin, Low-Molecular-Weight / therapeutic use*
  • Humans
  • Jugular Veins
  • Lung Neoplasms* / complications
  • Male
  • Mesenteric Artery, Superior
  • Mesenteric Vascular Occlusion / etiology
  • Mesenteric Vascular Occlusion / prevention & control
  • Middle Aged
  • Secondary Prevention
  • Subclavian Vein
  • Thrombosis / etiology
  • Thrombosis / prevention & control*
  • Tinzaparin
  • Treatment Failure
  • Venous Thromboembolism / etiology
  • Venous Thromboembolism / prevention & control*
  • Venous Thrombosis / etiology
  • Venous Thrombosis / prevention & control

Substances

  • Fibrinolytic Agents
  • Heparin, Low-Molecular-Weight
  • Tinzaparin