Abstract
In 2012, chikungunya virus (CHIKV) was reported for the first time in Bhutan. IgM ELISA results were positive for 36/210 patient samples; PCR was positive for 32/81. Phylogenetic analyses confirmed that Bhutan CHIKV belongs to the East/Central/South African genotype. Appropriate responses to future outbreaks require a system of surveillance and improved laboratory capacity.
Keywords:
Aedes aegypti; Aedes albopictus; Alphavirus; Bhutan; Chikungunya fever; Chikungunya virus; Togaviridae; outbreak; re-emerging disease; viruses.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adolescent
-
Adult
-
Aged
-
Alphavirus Infections / blood
-
Alphavirus Infections / epidemiology*
-
Alphavirus Infections / immunology
-
Amino Acid Sequence
-
Antibodies, Viral / blood
-
Bhutan / epidemiology
-
Chikungunya Fever
-
Chikungunya virus / genetics
-
Chikungunya virus / immunology*
-
Chikungunya virus / isolation & purification
-
Child
-
Child, Preschool
-
Disease Outbreaks*
-
Female
-
Humans
-
Immunoglobulin M / blood
-
Infant
-
Male
-
Middle Aged
-
Molecular Diagnostic Techniques
-
Molecular Sequence Data
-
Phylogeny
-
Reverse Transcriptase Polymerase Chain Reaction
-
Viral Envelope Proteins / genetics
-
Young Adult
Substances
-
Antibodies, Viral
-
Immunoglobulin M
-
Viral Envelope Proteins