Surgical management of effusive constrictive pericarditis

Cardiovasc J Afr. 2013 Sep;24(8):303-7. doi: 10.5830/CVJA-2013-042. Epub 2013 Sep 16.

Abstract

Objective: The surgical approach for effusive constrictive pericarditis (ECP) has not been extensively studied. We present our institution's early and long-term results of pericardiectomy in our cohort of patients with ECP.

Methods: Diagnosis was made primarily by echocardiography. Right heart catheterisation was performed in eight patients. Pre-operatively, 10 patients had undergone at least one previous attempt at therapeutic pericardiocentesis. Pericardiectomy was performed where appropriate (thickened or inflamed).

Results: Of our 12 patients (50% male, median age 48 years, range 17-72 years), the underlying aetiology included idiopathic in five (41.6%), tuberculosis in four (33%), and malignancy in three patients (25%). Elective surgery was performed in nine patients. Median values of both central venous pressure and pulmonary capillary wedge pressure decreased markedly postoperatively (from 16.5 to 11.0 mmHg, p = 0.02; 20.0-15.0 mmHg, p = 0.01, respectively). There was no in-hospital mortality. Follow up ranged from three months to nine years (median three years). Five (41.6%) patients died during the follow-up period, and cumulative two-year survival was 55.6 ± 1.5%.

Conclusions: Pericardiectomy for ECP was effective, in terms of our early results, in patients unresponsive to medical therapy. Long-term survival depends on the underlying disease.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cardiac Catheterization
  • Central Venous Pressure
  • Echocardiography
  • Elective Surgical Procedures
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pericardial Effusion / diagnosis
  • Pericardial Effusion / etiology
  • Pericardial Effusion / mortality
  • Pericardial Effusion / physiopathology
  • Pericardial Effusion / surgery*
  • Pericardiectomy* / adverse effects
  • Pericardiectomy* / mortality
  • Pericardiocentesis
  • Pericarditis, Constrictive / diagnosis
  • Pericarditis, Constrictive / etiology
  • Pericarditis, Constrictive / mortality
  • Pericarditis, Constrictive / physiopathology
  • Pericarditis, Constrictive / surgery*
  • Pulmonary Wedge Pressure
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Young Adult