Abstract
We report a pH-responsive gold nanoparticles-in-liposome hybrid nanostructure, which effectively combines the pH-responsive assembly and surface plasmon property changes of 'smart' gold nanoparticles and enhanced systemic circulation and tumor accumulation of the PEG-grafted liposomes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / administration & dosage*
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Antineoplastic Agents / pharmacology
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Cell Line, Tumor
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Cell Survival / drug effects
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Gold / chemistry*
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Gold / pharmacology
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Hydrogen-Ion Concentration
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Liposomes / chemistry*
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Liposomes / metabolism
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Melanoma, Experimental / metabolism
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Melanoma, Experimental / pathology
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Metal Nanoparticles / administration & dosage
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Metal Nanoparticles / chemistry*
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Mice
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Nanostructures / chemistry*
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Polyethylene Glycols / chemistry
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Surface Plasmon Resonance
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Tissue Distribution
Substances
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Antineoplastic Agents
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Liposomes
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Polyethylene Glycols
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Gold