Abstract
We determined the prevalence of seven clinically important pathogens that cause sexually transmitted infections (STIs) (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, herpes simplex virus 1 [HSV-1], HSV-2, and Treponema pallidum), by using a multiplex polymerase chain reaction (M-PCR) in samples from Brazilian woman infected with human immunodeficiency virus 1 (HIV-1) and uninfected Brazilian women (controls). The M-PCR assay identified all STIs tested for and surprisingly, occurred association between the control and STIs. This association was probably caused by excellent HIV infection control and regular monitoring in these women established by public health strategies in Brazil to combat HIV/acquired immunodeficiency syndrome. Studies using this M-PCR in different populations may help to better elucidate the roles of STIs in several conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Brazil / epidemiology
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Chlamydia trachomatis / genetics
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Chlamydia trachomatis / isolation & purification
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DNA Primers / genetics
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Female
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HIV Infections / complications
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HIV Infections / epidemiology*
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Herpesvirus 1, Human / genetics
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Herpesvirus 1, Human / isolation & purification
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Herpesvirus 2, Human / genetics
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Herpesvirus 2, Human / isolation & purification
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Humans
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Middle Aged
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Multiplex Polymerase Chain Reaction / methods*
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Mycoplasma genitalium / genetics
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Mycoplasma genitalium / isolation & purification
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Neisseria gonorrhoeae / genetics
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Neisseria gonorrhoeae / isolation & purification
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Prevalence
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Sexually Transmitted Diseases / diagnosis*
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Sexually Transmitted Diseases / epidemiology
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Treponema pallidum / genetics
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Treponema pallidum / isolation & purification
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Trichomonas vaginalis / genetics
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Trichomonas vaginalis / isolation & purification