Laparoscopically assisted biomaterial graft for reconstruction in congenital atresia of vagina and cervix

Fertil Steril. 2013 Dec;100(6):1784-7. doi: 10.1016/j.fertnstert.2013.08.046. Epub 2013 Sep 29.

Abstract

Objective: To report successful treatment by laparoscopically assisted biomaterial graft for reconstruction in patients with congenital atresia of the uterine cervix and vagina.

Design: Technique and instrumentations.

Setting: University-based tertiary care hospital.

Patient(s): An 18-year-old woman with vaginal agenesis and cervical dysgenesis and a 13-year-old woman with vaginal agenesis and cervical agenesis, both patients with a functional uterus.

Intervention(s): Creation of a neovagina by vaginal procedure and laparoscopically assisted biomaterial graft for uterovaginal anastomosis was performed in all patients.

Main outcome measure(s): All surgical findings were carefully reviewed to determine the anatomic characteristics of the malformed cervix. Subsequent follow-up was done by referring physicians.

Result(s): Uterovaginal continuity was established successfully in both patients, and all of the women were menstruating normally. Granulomatous polyps occurred in one patient, and this condition was successfully managed. At 6-month follow-up, mean vaginal length was 12 cm and ≥ 80% of neovaginal epithelium was iodine positive in both patients. Unimpeded menstrual flow continued after 4 years of follow-up in one patient and 5 years of follow-up in the other patient.

Conclusion(s): A combined laparoscopic and vaginal procedure with biomaterial graft could be an effective alternative in selected women with atresia of cervix and vagina.

Keywords: Cervical atresia; biomaterial graft; laparoscopy; uterovaginal anastomosis; vagina agenesis.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Adolescent
  • Anastomosis, Surgical / instrumentation
  • Anastomosis, Surgical / methods*
  • Cervix Uteri / abnormalities*
  • Cervix Uteri / pathology
  • Cervix Uteri / surgery*
  • Combined Modality Therapy
  • Female
  • Gynecologic Surgical Procedures / instrumentation
  • Gynecologic Surgical Procedures / methods
  • Humans
  • Laparoscopy / instrumentation
  • Laparoscopy / methods*
  • Plastic Surgery Procedures / instrumentation
  • Plastic Surgery Procedures / methods*
  • Prostheses and Implants
  • Treatment Outcome
  • Vagina / abnormalities*
  • Vagina / pathology
  • Vagina / surgery*
  • Young Adult