Abstract
The effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.
MeSH terms
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Anticholesteremic Agents / administration & dosage*
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Antihypertensive Agents / adverse effects*
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Cardiovascular Diseases / drug therapy*
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Female
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Humans
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Male
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Medication Adherence / statistics & numerical data*
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Platelet Aggregation Inhibitors / administration & dosage*
Substances
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Anticholesteremic Agents
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Antihypertensive Agents
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Platelet Aggregation Inhibitors