Prevention: Polypills for cardiovascular prevention: a step forward?

Nat Rev Cardiol. 2013 Dec;10(12):683-4. doi: 10.1038/nrcardio.2013.157. Epub 2013 Oct 8.

Abstract

The effect of a fixed-dose combination drug strategy ('polypill') on patients' adherence to medication was analysed in a series of 2,004 individuals with, or at high risk of, cardiovascular disease in the UMPIRE study. The polypill improved adherence by >20%, but the reduction in blood-pressure and cholesterol levels was modest.

Publication types

  • News
  • Comment

MeSH terms

  • Anticholesteremic Agents / administration & dosage*
  • Antihypertensive Agents / adverse effects*
  • Cardiovascular Diseases / drug therapy*
  • Female
  • Humans
  • Male
  • Medication Adherence / statistics & numerical data*
  • Platelet Aggregation Inhibitors / administration & dosage*

Substances

  • Anticholesteremic Agents
  • Antihypertensive Agents
  • Platelet Aggregation Inhibitors