Innovative techniques in evaluating the esophagus; imaging of esophageal morphology and function; and drugs for esophageal disease

Ann N Y Acad Sci. 2013 Oct:1300:11-28. doi: 10.1111/nyas.12233.

Abstract

This paper reporting on techniques for esophageal evaluation and imaging and drugs for esophageal disease includes commentaries on endoscopy techniques including dye-based high-resolution and dye-less high-definition endoscopy; the shift from CT to MRI guidance in tumor delineation for radiation therapy; the role of functional lumen imaging in measuring esophageal distensibility; electrical stimulation of the lower esophageal sphincter (LES) as an alternative to fundoduplication for treatment of gastroesophageal reflux disease (GERD); the morphological findings of reflux esophagitis and esophageal dysmotility on double-contrast esophagography; the value of videofluoroscopy in assessing protecting mechanisms in patients with chronic reflux or swallowing disorders; targeting visceral hypersensitivity in the treatment of refractory GERD; and the symptoms and treatments of nighttime reflux and nocturnal acid breakthrough (NAB).

Keywords: EndoStim; Endoscopy; FLIP; GERD; PPI; nighttime breakthrough; swallowing; videofluoroscopy.

Publication types

  • Review

MeSH terms

  • Deglutition / physiology*
  • Diagnostic Imaging
  • Esophageal Diseases / diagnosis*
  • Esophageal Diseases / pathology
  • Esophageal Diseases / physiopathology
  • Esophageal Diseases / therapy
  • Esophagoscopy
  • Esophagus / pathology*
  • Esophagus / physiopathology
  • Humans
  • Radiosurgery