Tissue resistance in the normal and diseased esophagus

Andrew M Bellizzi; Gerardo Nardone; Debora Compare; Serhat Bor; Doga Capanoglu; Ricard Farré; Helmut Neumann; Markus F Neurath; Michael Vieth; Hao Chen; Xiaoxin Chen

doi:10.1111/nyas.12248

Tissue resistance in the normal and diseased esophagus

Ann N Y Acad Sci. 2013 Oct:1300:200-212. doi: 10.1111/nyas.12248.

Authors

Andrew M Bellizzi¹, Gerardo Nardone², Debora Compare², Serhat Bor³, Doga Capanoglu³, Ricard Farré⁴, Helmut Neumann⁵, Markus F Neurath⁵, Michael Vieth⁶, Hao Chen⁷, Xiaoxin Chen^{7

8}

Affiliations

¹ Department of Pathology, University of Iowa Hospitals and Clinics, University of Iowa Carver College of Medicine, Iowa City, Iowa.
² Department of Clinical and Experimental Medicine, Gastroenterology Unit, University "Federico II", Naples, Italy.
³ Sect Gastroenterology, Ege Reflux Study Group, Ege University School of Medicine, Bornova, Turkey.
⁴ Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium.
⁵ Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany.
⁶ Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany.
⁷ Cancer Research Program, JLC-BBRI, North Carolina Central University, Durham, North Carolina.
⁸ Division of Gastroenterology and Hepatology, Department of Medicine, Center for Esophageal Diseases and Swallowing, University of North Carolina, Chapel Hill, North Carolina.

PMID: 24117643
DOI: 10.1111/nyas.12248

Abstract

This paper presents commentaries on reflux-induced injury of human esophageal epithelium; inflammation in human reflux esophagitis; motor consequences of reflux-induced inflammation in esophageal epithelium; the microscopic morphology of esophageal squamous epithelium; intraluminal impedance in the evaluation of the esophageal mucosa; endoscopic tissue morphology of esophageal squamous epithelium; and the developmental biology of esophageal squamous epithelium.

Keywords: GERD; eosinophilic esophagitis; erosive esophagitis; esophageal squamous epithelium.

Publication types

Review

MeSH terms

Barrett Esophagus / etiology
Barrett Esophagus / pathology*
Esophagitis, Peptic / etiology
Esophagitis, Peptic / pathology*
Esophagus / pathology*
Gastroesophageal Reflux / complications
Gastroesophageal Reflux / pathology*
Humans
Mucous Membrane / pathology