Abstract
Surgery and antifungals are the reference standard for rhino-orbito-cerebral mucormycosis (ROCM) treatment. The impact of local control on survival of 22 consecutive ROCM adults was studied on day 90: none vs. 75% died, respectively, with or without local control (p <0.0001). Hence, repeated surgical procedures are recommended to achieve local control of ROCM.
Keywords:
Local control; mucormycosis; necrosis; sinusitis; surgery.
© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antifungal Agents / therapeutic use
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Bone Diseases, Infectious / microbiology
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Bone Diseases, Infectious / mortality
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Bone Diseases, Infectious / therapy*
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Brain Diseases / microbiology
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Brain Diseases / therapy
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Combined Modality Therapy / methods
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Debridement / methods*
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Female
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Humans
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Male
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Middle Aged
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Mucormycosis / mortality
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Mucormycosis / therapy*
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Orbital Diseases / microbiology
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Orbital Diseases / mortality
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Orbital Diseases / therapy*
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Paranasal Sinus Diseases / microbiology
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Paranasal Sinus Diseases / mortality
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Paranasal Sinus Diseases / therapy*
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Retrospective Studies
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Skull Base / surgery
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Survival Rate
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Young Adult