Evaluation of the chronic obstructive pulmonary disease assessment test in Japanese outpatients

Clin Respir J. 2014 Apr;8(2):213-9. doi: 10.1111/crj.12062. Epub 2014 Jan 15.

Abstract

Objective: The Chronic Obstructive Pulmonary Disease (COPD) Assessment Test (CAT) is a quality-of-life (QOL) questionnaire that proved to correlate with St. George's Respiratory Questionnaire. Correlations between CAT scores and other COPD parameters have not been thoroughly evaluated in Japanese outpatients.

Methods: Cross-sectional study of 85 outpatients with COPD at a Japanese community-based hospital.

Patients: We observed 70 men and 15 women, whose average age was 72.0 ± 9.0 years. Mean forced expiratory volume in 1 s (FEV1) (% predicted) was 45.8 ± 14.7%. Mean CAT score was 10.1 ± 7.9 (range: 0-31). We calculated Spearman's rank correlation coefficient for CAT score and the following variables: r=0.81 for 'the Body Mass Index, Airflow Obstruction, Dyspnea and Exercise Capacity Index'; r=-0.05 for body mass index; r=-0.56 for FEV1 (% predicted); r=0.88 for Modified Medical Research Council Dyspnea Scale; r=-0.71 for 6-min walk distance; r=0.68 for 'the Age, Dyspnoea,and Airflow Obstruction Index'; and r=-0.40 for oxygen saturation in artery. Each COPD parameter, except for body mass index, had a significant (P<0.001) correlation with the CAT score.

Conclusions: The CAT score, which is obtainable by a simple questionnaire originally designed for QOL assessment, had strong correlations with airflow obstruction, dyspnea, exercise tolerance, prognostic index and oxygenation in Japanese outpatients.

Keywords: dyspnea; exercise tolerance; quality of life; questionnaires; spirometry.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Japan / epidemiology
  • Male
  • Morbidity / trends
  • Outpatients*
  • Prognosis
  • Pulmonary Disease, Chronic Obstructive / diagnosis*
  • Pulmonary Disease, Chronic Obstructive / epidemiology
  • Respiratory Function Tests / methods*
  • Retrospective Studies
  • Severity of Illness Index
  • Surveys and Questionnaires