Systemic capillary leak syndrome: recognition prevents morbidity and mortality

D J Rabbolini; N Ange; G D Walters; M Pidcock; K L Randall

doi:10.1111/imj.12271

Systemic capillary leak syndrome: recognition prevents morbidity and mortality

Intern Med J. 2013 Oct;43(10):1145-7. doi: 10.1111/imj.12271.

Authors

D J Rabbolini¹, N Ange, G D Walters, M Pidcock, K L Randall

Affiliation

¹ Department of Haematology, The Canberra Hospital, Canberra, Australian Capital Territory, Australia.

PMID: 24134172
DOI: 10.1111/imj.12271

Abstract

Idiopathic systemic capillary leak syndrome (SCLS) is extremely rare but carries a high morbidity and mortality. The diagnosis is made clinically by a classic triad of hypotension, hypoalbuminaemia and haemoconcentration. There have been recent advances in understanding the pathophysiological basis for SCLS and in effective prophylaxis. We report a case of SCLS to increase awareness of the condition and to highlight the benefits of prophylactic intravenous immunoglobulin in this condition.

Keywords: intravenous immunoglobulin; oedema; polycythaemia; shock; systemic capillary leak syndrome.

Publication types

Case Reports

MeSH terms

Capillary Leak Syndrome / blood*
Capillary Leak Syndrome / diagnosis*
Capillary Leak Syndrome / drug therapy
Humans
Immunoglobulins, Intravenous / therapeutic use*
Male
Middle Aged
Morbidity

Substances

Immunoglobulins, Intravenous