Sampling scheme and compressed sensing applied to solid-state NMR spectroscopy

J Magn Reson. 2013 Dec:237:40-48. doi: 10.1016/j.jmr.2013.09.013. Epub 2013 Oct 1.

Abstract

We describe the incorporation of non-uniform sampling (NUS) compressed sensing (CS) into oriented sample (OS) solid-state NMR for stationary aligned samples and magic angle spinning (MAS) Solid-state NMR for unoriented 'powder' samples. Both simulated and experimental results indicate that 25-33% of a full linearly sampled data set is required to reconstruct two- and three-dimensional solid-state NMR spectra with high fidelity. A modest increase in signal-to-noise ratio accompanies the reconstruction.

Keywords: Compressed sensing; Membrane proteins; Non-uniform sampling; Oriented samples; Protein NMR; Sensitivity; Solid-state NMR.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Computer Simulation
  • Data Interpretation, Statistical
  • Magnetic Resonance Spectroscopy / methods*
  • Poisson Distribution
  • Powders
  • Reproducibility of Results
  • Signal-To-Noise Ratio

Substances

  • Powders