Does intramesorectal proctectomy with rectal eversion affect postoperative complications compared to standard total mesorectal excision in patients with ulcerative colitis?

J Gastrointest Surg. 2014 Feb;18(2):385-90. doi: 10.1007/s11605-013-2359-2. Epub 2013 Oct 22.

Abstract

Introduction: Proctectomy for ulcerative colitis (UC) can be performed via intramesorectal proctectomy with concomitant rectal eversion (IMP/RE) or total mesorectal excision (TME). No data exists comparing the outcomes of the two techniques.

Methods: All UC patients undergoing J-pouch surgery at a single institution over 10.5 years were included. Postoperative complications with IMP/RE vs. TME were analyzed using univariable and multivariable statistics.

Results: One hundred nineteen of 201 (59 %) patients underwent IMP/RE. Demographic and disease characteristics were similar between groups. On univariable analysis, IMP/RE had fewer total perioperative complications than TME (p = 0.02), but no differences in postoperative length of stay or readmissions. Multivariable regression accounting for patient age, comorbidities, disease severity, preoperative medications, operative technique, and follow-up time (mean 5.5 ± 0.2 years) suggested that both anastomotic leak rate (OR 0.32; p = 0.04) and overall postoperative complications (2.10 ± 0.17 vs. 2.60 ± 0.20; p = 0.05) were lower in the IMP/RE group.

Conclusions: IMP/RE may be associated with fewer overall postoperative complications compared to TME. However, further studies on functional and long-term outcomes are needed.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anastomotic Leak / etiology*
  • Child
  • Colitis, Ulcerative / surgery*
  • Colonic Pouches / adverse effects*
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Length of Stay
  • Male
  • Middle Aged
  • Patient Readmission
  • Postoperative Complications / etiology
  • ROC Curve
  • Rectum / surgery*
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Young Adult

Substances

  • Immunosuppressive Agents