Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment

Leukemia. 2014 Feb;28(2):460-3. doi: 10.1038/leu.2013.303. Epub 2013 Oct 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Clonal Evolution
  • Haplotypes*
  • Hematopoietic Stem Cells / drug effects
  • Hematopoietic Stem Cells / metabolism
  • Humans
  • Interferon-alpha / therapeutic use
  • Janus Kinase 2 / genetics*
  • Models, Biological
  • Mutation*
  • Polycythemia Vera / drug therapy
  • Polycythemia Vera / genetics*
  • Polycythemia Vera / metabolism*

Substances

  • Interferon-alpha
  • Janus Kinase 2