Usefulness of FDG PET/CT in the diagnosis of eosinophilic fasciitis

Clin Nucl Med. 2014 Sep;39(9):801-2. doi: 10.1097/RLU.0000000000000260.

Abstract

Eosinophilic fasciitis is a rare disorder with similar characteristics of scleroderma-like illness. We report a case of eosinophilic fasciitis in a 37-year-old woman with a 3-month history of progressive stiffness involving her forearms and lower legs. Laboratory test disclosed elevated erythrocyte sedimentation ratio and hypereosinophilia. On PET/CT images, FDG uptake was increased along the fasciae of bilateral upper and lower extremities while sparing muscles and subcutaneous fat. Biopsy was performed and histologic examination confirmed diagnosis of eosinophilic fasciitis. FDG PET/CT may be helpful in the diagnosis of eosinophilic fasciitis as it could clearly illustrate anatomical involvement of the disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia / diagnostic imaging*
  • Fasciitis / diagnostic imaging*
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Multimodal Imaging*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Tomography, X-Ray Computed*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18

Supplementary concepts

  • Eosinophilic Fasciitis