Role of acetylcholine receptor subunits in gating of the channel

Nature. 1985 Dec;318(6046):538-43. doi: 10.1038/318538a0.

Abstract

The Torpedo and calf acetylcholine receptors and hybrids composed of subunits from the two species have been produced in Xenopus oocytes by the use of the cloned complementary DNAs. Single-channel current measurements indicate that these receptors form channels of similar conductance but with different gating behaviour.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Electric Conductivity
  • Ion Channels / physiology*
  • Macromolecular Substances
  • Oocytes
  • Receptors, Nicotinic / physiology*
  • Structure-Activity Relationship
  • Torpedo
  • Xenopus

Substances

  • Ion Channels
  • Macromolecular Substances
  • Receptors, Nicotinic