Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood

Blood. 2013 Oct 24;122(17):3088-9. doi: 10.1182/blood-2013-07-515973.
No abstract available

MeSH terms

  • Basic Helix-Loop-Helix Transcription Factors / blood*
  • Basic Helix-Loop-Helix Transcription Factors / genetics
  • Case-Control Studies
  • Erythropoietin / blood
  • Erythropoietin / genetics
  • Fetal Hemoglobin / genetics
  • Fetal Hemoglobin / metabolism*
  • Gene Expression Regulation
  • Heterozygote
  • Homozygote
  • Humans
  • Hypoxia-Inducible Factor 1 / blood*
  • Hypoxia-Inducible Factor 1 / genetics
  • Mutation
  • Polycythemia / blood
  • Polycythemia / congenital*
  • Polycythemia / genetics
  • Polycythemia / pathology
  • Von Hippel-Lindau Tumor Suppressor Protein / blood
  • Von Hippel-Lindau Tumor Suppressor Protein / genetics

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • EPO protein, human
  • Hypoxia-Inducible Factor 1
  • Erythropoietin
  • endothelial PAS domain-containing protein 1
  • Fetal Hemoglobin
  • Von Hippel-Lindau Tumor Suppressor Protein
  • VHL protein, human

Supplementary concepts

  • Erythrocytosis, Familial, 2