A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity

Br J Haematol. 2014 Jan;164(2):304-7. doi: 10.1111/bjh.12617. Epub 2013 Oct 26.
No abstract available

Keywords: CD47; apoptosis; phagocytosis; rituximab; tumor necrosis factor-related apoptosis-inducing ligand.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / immunology
  • Antibodies, Monoclonal / pharmacology*
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects*
  • CD47 Antigen / immunology*
  • Humans
  • Phagocytosis / drug effects*
  • Recombinant Fusion Proteins / pharmacology*
  • TNF-Related Apoptosis-Inducing Ligand / antagonists & inhibitors
  • TNF-Related Apoptosis-Inducing Ligand / immunology*

Substances

  • Antibodies, Monoclonal
  • Antineoplastic Agents
  • CD47 Antigen
  • Recombinant Fusion Proteins
  • TNF-Related Apoptosis-Inducing Ligand