Causative role of infection in chronic non-thromboembolic pulmonary hypertension following ventriculo-atrial shunt

Br J Neurosurg. 2014 Aug;28(4):559-61. doi: 10.3109/02688697.2013.854311. Epub 2013 Nov 1.

Abstract

A severe complication of ventriculo-atrial (VA) shunt placement for treatment of hydrocephalus is chronic thromboembolic pulmonary hypertension (CTEPH). We report here a patient with a VA shunt for treatment of hydrocephalus who presented two consecutive episodes of VA shunt-induced infection by Staphylococcus epidermidis and who rapidly developed chronic PH. Extensive radiological investigations and normal ventilation/perfusion lung scan allowed us to rule out CTEPH. To our knowledge, no other case of chronic pulmonary hypertension (PH) related to VA shunt insertion has been reported so far. PH in this patient with VA shunt is clinically distinct from CTEPH and has been caused by VA shunt-induced S. epidermidis infection per se.

Keywords: VA-shunt; hydrocephaly; infectious; pulmonary hypertension.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebrospinal Fluid Shunts / adverse effects*
  • Chronic Disease
  • Humans
  • Hydrocephalus / diagnosis
  • Hydrocephalus / surgery*
  • Hypertension, Pulmonary / etiology
  • Hypertension, Pulmonary / surgery*
  • Male
  • Staphylococcal Infections / therapy*
  • Staphylococcus epidermidis / isolation & purification*
  • Treatment Outcome