A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia

Leukemia. 2014 Feb;28(2):436-9. doi: 10.1038/leu.2013.289. Epub 2013 Oct 9.

Authors

P Sportoletti¹, S Baldoni¹, B Del Papa¹, P Aureli¹, E Dorillo¹, L Ruggeri¹, S Plebani², V Amico², A Di Tommaso², E Rosati³, P Marconi³, M Di Ianni², F Falzetti¹

Affiliations

¹ Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
² Hematology Section, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
³ General Pathology and Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

PMID: 24177259
DOI: 10.1038/leu.2013.289

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Alleles*
Disease Progression
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / mortality*
Mutation Rate*
Prognosis
Receptor, Notch1 / genetics*

Substances

Receptor, Notch1