Pediatric tectal plate gliomas: clinical and radiological progression, MR imaging characteristics, and management of hydrocephalus

J Neurosurg Pediatr. 2014 Jan;13(1):13-20. doi: 10.3171/2013.9.PEDS13347. Epub 2013 Nov 1.

Abstract

Object: Tectal plate gliomas are generally low-grade astrocytomas with favorable prognosis, and observation of the lesion and management of hydrocephalus remain the mainstay of treatment.

Methods: A cohort of patients with tectal plate gliomas at 2 academic institutions was retrospectively reviewed.

Results: Forty-four patients with a mean age of 10.2 years who harbored tectal plate gliomas were included in the study. The mean clinical and radiological follow-up was 7.6 ± 3.3 years (median 7.9 years, range 1.5-14.7 years) and 6.5 ± 3.1 years (median 6.5 years, range 1.1-14.7 years), respectively. The most frequent intervention was CSF diversion (81.8% of patients) followed by biopsy (11.4%), radiotherapy (4.5%), chemotherapy (4.5%), and resection (2.3%). On MR imaging tectal plate gliomas most commonly showed T1-weighted isointensity (71.4%), T2-weighted hyperintensity (88.1%), and rarely enhanced (19%). The initial mean volume was 1.6 ± 2.2 cm(3) and it increased to 2.0 ± 4.4 cm(3) (p = 0.628) at the last follow-up. Frontal and occipital horn ratio (FOHR) and third ventricular width statistically decreased over time (p < 0.001 and p < 0.05, respectively).

Conclusions: The authors' results support existing evidence that tectal plate gliomas frequently follow a benign clinical and radiographic course and rarely require any intervention beyond management of associated hydrocephalus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Academic Medical Centers
  • Adolescent
  • Brain Stem Neoplasms / complications
  • Brain Stem Neoplasms / diagnosis*
  • Brain Stem Neoplasms / diagnostic imaging
  • Child
  • Child, Preschool
  • Disease Progression
  • Female
  • Follow-Up Studies
  • Glioma / complications
  • Glioma / diagnosis*
  • Glioma / diagnostic imaging
  • Humans
  • Hydrocephalus / etiology*
  • Hydrocephalus / surgery*
  • Magnetic Resonance Imaging*
  • Male
  • Radiography
  • Retrospective Studies
  • Tectum Mesencephali* / diagnostic imaging
  • Tectum Mesencephali* / pathology
  • Young Adult