Safety and long-term efficacy of endovascular treatment of small posterior communicating artery aneurysms by coiling with or without stent: a single center retrospective study

Clin Neurol Neurosurg. 2013 Dec;115(12):2502-7. doi: 10.1016/j.clineuro.2013.10.005. Epub 2013 Oct 16.

Abstract

Objectives: Endovascular stents have been widely used in intracranial aneurysm embolization. In this work, we compared the safety and long-term efficacy of stent-assisted coiling with those of conventional coiling for small posterior communicating artery aneurysms, aiming at a better understanding of the related safety and efficacy profiles.

Methods: Between January 2008 and December 2011, 114 small PcomA aneurysms (defined as 3mm≤maximum diameter<10mm in this study) in 108 patients were treated by endovascular treatment in our department. Patient demographics, aneurysm characteristics, angiographic results (initial and follow-up), and procedural complications were assessed.

Results: Embolization was successfully performed in all the patients. Complications occurred in 7.4% of patients in both groups. There was no associated mortality. Based on initial post-procedural angiography, the rate of complete aneurysm occlusion, neck remnant and residual sac in the stented group were 37.9%, 24.1%, and 37.9%, while in the conventional group the figures were 42.9%, 48.2%, and 8.9%, respectively. The initial angiographic results were significantly better in the conventional group, compared with the stented group (P=0.038). The follow-up results showed that the rate of improvement in the stented group was significantly higher (53.3% vs. 14.0%; P<0.001) and the recurrence rate was significantly lower than that in the conventional group (4.4% vs. 3.02%; P=0.001).

Conclusion: Compared with conventional coiling, stent-assisted coiling of the small posterior communicating artery aneurysms does not increase the risk. Stents bear an advantage in reducing the recurrence rate, increasing progressive occlusion rate, and improving long-term prognosis in endovascular treatment of intracranial aneurysms.

Keywords: Embolization; Intracranial aneurysm; Posterior communicating artery; Stents.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography, Digital Subtraction
  • Cerebral Angiography
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / methods*
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / methods*
  • Female
  • Follow-Up Studies
  • Graft Occlusion, Vascular / epidemiology
  • Humans
  • Intracranial Aneurysm / surgery*
  • Male
  • Middle Aged
  • Perioperative Care
  • Postoperative Complications / epidemiology
  • Postoperative Complications / therapy
  • Retrospective Studies
  • Stents*
  • Treatment Outcome