Immunocytochemical study of a trabecular carcinoma of the skin (Merkel cell tumor). Case report

F Carlei; D Lomanto; S Chimenti; G Pranteda; G Castagna; E Lezoche; P Mariani; M D D'Alessandro; S E Gendel; V Speranza

Immunocytochemical study of a trabecular carcinoma of the skin (Merkel cell tumor). Case report

Ital J Surg Sci. 1986;16(1):55-9.

Authors

F Carlei, D Lomanto, S Chimenti, G Pranteda, G Castagna, E Lezoche, P Mariani, M D D'Alessandro, S E Gendel, V Speranza

PMID: 2424864

Abstract

The existence of different neuroendocrine markers was investigated by immunocytochemistry in a case of Merkel cells tumor. Neuroplastic cells contain NSE,NF,CK and chromogranin A i.r. On the basis of the results the neuroendocrine nature of this uncommon neoplasm of the skin is confirmed and it is suggested that chromogranin A could represent an additional marker for Merkel cells tumors.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / immunology
Adenocarcinoma / metabolism*
Adenocarcinoma / pathology
Aged
Chromogranin A
Chromogranins / metabolism
Humans
Immunoenzyme Techniques
Intermediate Filaments / metabolism
Keratins / metabolism
Lymphatic Metastasis
Male
Phosphopyruvate Hydratase / metabolism
Skin Neoplasms / immunology
Skin Neoplasms / metabolism*
Skin Neoplasms / pathology
Staining and Labeling

Substances

Chromogranin A
Chromogranins
Keratins
Phosphopyruvate Hydratase