Primaquine for prophylaxis of malaria: has the CYP sailed?

J Travel Med. 2014 Jan-Feb;21(1):67-9. doi: 10.1111/jtm.12080. Epub 2013 Nov 19.

Authors

Gregory A Deye¹, Alan J Magill

Affiliation

¹ Division of Microbiology and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

PMID: 24251618
DOI: 10.1111/jtm.12080

No abstract available

MeSH terms

Antimalarials / pharmacokinetics
Antimalarials / therapeutic use
Biotransformation
Chemoprevention / methods
Cytochrome P-450 Enzyme System / metabolism*
Drug Resistance / physiology*
Humans
Isoenzymes
Malaria* / metabolism
Malaria* / prevention & control
Post-Exposure Prophylaxis / methods
Primaquine* / pharmacokinetics
Primaquine* / therapeutic use
Secondary Prevention
Travel
Treatment Outcome

Substances

Antimalarials
Isoenzymes
Cytochrome P-450 Enzyme System
Primaquine