A case of cutaneous polyarteritis nodosa with elevated serum interleukin-6 levels complicated by leg arterial stenosis and destructive arthropathy of the left ankle

Mod Rheumatol. 2014 Jan;24(1):206-11. doi: 10.3109/14397595.2013.852840.

Abstract

We report a case of a 60-year-old female with cutaneous polyarteritis nodosa (CPN) of the left ankle, accompanied by elevated serum interleukin (IL)-6 levels. Computed tomographic angiography revealed severe narrowing of medium-sized arteries in her left leg. Destructive arthropathy in the left ankle was identified by X-ray and magnetic resonance imaging. This is the first Japanese case of severe CPN complicated by destructive arthropathy. Quantification of serum IL-6 might be useful in diagnosis and evaluation of CPN.

Publication types

  • Case Reports

MeSH terms

  • Ankle / diagnostic imaging*
  • Ankle / pathology
  • Ankle Joint / diagnostic imaging*
  • Ankle Joint / pathology
  • Arteriosclerosis / blood
  • Arteriosclerosis / complications*
  • Arteriosclerosis / diagnostic imaging
  • Arteriosclerosis / pathology
  • Constriction, Pathologic / blood
  • Constriction, Pathologic / complications
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / pathology
  • Female
  • Humans
  • Interleukin-6 / blood*
  • Leg / diagnostic imaging
  • Leg / pathology
  • Middle Aged
  • Polyarteritis Nodosa / blood
  • Polyarteritis Nodosa / complications*
  • Polyarteritis Nodosa / diagnostic imaging
  • Polyarteritis Nodosa / pathology
  • Radiography
  • Skin / pathology*

Substances

  • Interleukin-6