Abstract
After PCV7 implementation, clinical characteristics were investigated in 832 young children with acute otitis media, carrying a single S. pneumoniae or H. influenzae in their nasopharynx. As compared with H. influenzae, S. pneumoniae-associated acute otitis media was less frequently associated with treatment failure (odds ratio = 0.5; 95% confidence interval: 0.36-0.83) and recurrence (odds ratio = 0.4; 95% confidence interval: 0.22-0.75). Post-PCV7 serotype replacement seemed not to affect the acute otitis media characteristics in these children.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carrier State / epidemiology
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Carrier State / microbiology
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Female
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Haemophilus Infections / epidemiology*
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Haemophilus Infections / microbiology
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Haemophilus Infections / pathology*
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Haemophilus influenzae
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Heptavalent Pneumococcal Conjugate Vaccine
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Humans
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Infant
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Male
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Nasopharynx / microbiology*
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Otitis Media / epidemiology*
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Otitis Media / microbiology
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Otitis Media / pathology*
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / microbiology
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Pneumococcal Infections / pathology*
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Pneumococcal Vaccines / administration & dosage
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Recurrence
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Streptococcus pneumoniae
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Treatment Outcome
Substances
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Heptavalent Pneumococcal Conjugate Vaccine
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Pneumococcal Vaccines