An unusual suspect in cocaine addiction

Neuron. 2013 Nov 20;80(4):835-6. doi: 10.1016/j.neuron.2013.11.001.

Abstract

Development of drug addiction is extremely complex, but its initiation can be as simple as the flip-flop of glutamatergic receptor subtypes triggered by an "unusual" type of NMDA receptors, as suggested by Yuan et al. (2013) in this issue of Neuron.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cocaine / pharmacology*
  • Dopamine Uptake Inhibitors / pharmacology*
  • Female
  • Male
  • Neuronal Plasticity / drug effects*
  • Receptors, N-Methyl-D-Aspartate / physiology*
  • Synapses / drug effects*

Substances

  • Dopamine Uptake Inhibitors
  • GluN3A protein, mouse
  • Receptors, N-Methyl-D-Aspartate
  • Cocaine