Objectives: To compare pregnancy outcomes after transabdominal chorionic villus sampling using biopsy forceps or needle.
Materials and methods: Retrospective bicentric study including all women who had a transabdominal chorionic villus sampling between 2005 and 2009 (172 using biopsy forceps and 160 using needle). The primary endpoint was the rate of fetal loss, after excluding medical abortion due to the result of the biopsy. The secondary endpoint was the rate of premature rupture of the membrane. All cases were reviewed to try to determine the responsibility of the biopsy.
Results: The pregnancy outcomes were not different between the two groups: 4 (4.4%) fetal losses in the biopsy forceps group and 6 (7.4%) in the needle group (P=0.52). Only one case (1.2%) of fetal loss can be attributed to the biopsy, using a needle, and none (0%) following a forceps biospy (P=0.29). The rate of premature rupture of the membrane was comparable in the two groups.
Conclusion: The pregnancy outcomes following chorionic villus sampling using a biopsy forceps or a needle seem comparable.
Keywords: Biopsie de trophoblaste; Chorionic villus sampling; Fetal loss; Perte fœtale; Premature rupture of the membrane; Rupture prématurée des membranes.
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