An Italian consensus for invasive candidiasis management (ITALIC)

Infection. 2014 Apr;42(2):263-79. doi: 10.1007/s15010-013-0558-0. Epub 2013 Nov 25.

Abstract

Introduction: Invasive candidiasis (IC) has primarily been studied in intensive care unit (ICU) patients, although, in reality, a vast majority of these infections occur outside of the ICU. The recent publication of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines also deal with the non-ICU population, but many uncertainties remain on the management of IC, particularly in non-critically ill patients.

Methods: The Italian Society of Antimicrobial Therapy, Società Italiana di Terapia Antimicrobica (SITA), produced practical, hospital-wide recommendations on the management of Candida infection in non-immunocompromised patients in the hospital ward.

Results and discussion: Our focus is on patient stratification in terms of risk factors for IC and of clinical severity, emphasising a high index of suspicion to ensure early diagnosis, early treatment and de-escalation when a patient is clinically stable, in order to optimise resource allocation.

Publication types

  • Practice Guideline
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Candidiasis, Invasive / diagnosis
  • Candidiasis, Invasive / drug therapy*
  • Candidiasis, Invasive / epidemiology
  • Candidiasis, Invasive / prevention & control
  • Consensus
  • Humans
  • Italy / epidemiology
  • Risk Factors

Substances

  • Antifungal Agents