Invasive filamentous fungus infection with secondary cerebral vasculitis in a patient with no obvious immune suppression

Filippo Mearelli; Alessandro Occhipinti; Nicola Altamura; Giovanni Fernandes; Giulia Pivetti; Enrico Chendi; AnnaLisa Spalluti; Lorenza Mamolo; Chiara Casarsa; Gianni Biolo

doi:10.1016/j.ijid.2013.10.002

Invasive filamentous fungus infection with secondary cerebral vasculitis in a patient with no obvious immune suppression

Int J Infect Dis. 2014 Feb:19:91-2. doi: 10.1016/j.ijid.2013.10.002. Epub 2013 Nov 22.

Affiliations

¹ Clinica Medica Generale e Terapia Medica, Department of Medical, Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, 34149 Cattinara Trieste, Italy. Electronic address: [email protected].
² Clinica Medica Generale e Terapia Medica, Department of Medical, Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, 34149 Cattinara Trieste, Italy.

PMID: 24275049
DOI: 10.1016/j.ijid.2013.10.002

Abstract

Invasive mold infections represent an emerging and important diagnostic challenge, especially in immunocompetent patients when microscopy and cultures of the biological fluids remain negative. A central nervous system localization is not common and the clinical presentation is aspecific.

Keywords: CNS leukocytoclastic vasculitis; Fever of unknown origin; Invasive mold infections.

Publication types

Case Reports

MeSH terms

Diagnosis, Differential
Fatal Outcome
Female
Fever of Unknown Origin / etiology*
Fungi / cytology
Fungi / isolation & purification*
Humans
Invasive Pulmonary Aspergillosis / complications*
Invasive Pulmonary Aspergillosis / pathology
Italy
Middle Aged
Vasculitis, Central Nervous System / complications*
Vasculitis, Central Nervous System / pathology