Acute pulmonary embolism is one of the most frequent and risky cardiovascular diseases. Despite accessability of different examinig methods and rich clinical experience, pulmonary embolism is demanding disease especially in diagnostics. The reason might be in clinical picture, that is not typical everytime and leads to incorrect choice of diagnostic methods, that delay the disease assessment. Regarding this, precise evaluation of every each symptom and basal, resp. supplemental examinations is important step to rapid and right assessment of this diagnose.