Myasthenia gravis and thymoma coexisting with myotonic dystrophy type 1

Neuromuscul Disord. 2014 Jan;24(1):40-2. doi: 10.1016/j.nmd.2013.09.001. Epub 2013 Sep 11.

Abstract

We describe a 34-year old man presenting with subacute generalized myasthenic symptoms. His clinical features and laboratory investigations demonstrated both myasthenia gravis and myotonic dystrophy type 1. The computerized tomography of chest revealed anterior mediastinal mass. The lymphocyte-rich thymoma was removed surgically and he received radiotherapy. Recent observations suggested that the patients with myotonic dystrophy may have an increased risk of benign and malignant tumours but its coexistence with thymoma is very rare. The risk of thymoma associated with myotonic dystrophy is unknown.

Keywords: Myotonic dystrophy; Neoplasm; Thymoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Male
  • Myasthenia Gravis / complications
  • Myasthenia Gravis / diagnosis*
  • Myotonic Dystrophy / complications
  • Myotonic Dystrophy / diagnosis*
  • Risk Factors
  • Thymoma / complications
  • Thymoma / diagnosis*
  • Thymus Neoplasms / complications
  • Thymus Neoplasms / diagnosis*