Activation of xenobiotics by human polymorphonuclear leukocytes via reactive oxygen-dependent reactions

Adv Exp Med Biol. 1986:197:311-21. doi: 10.1007/978-1-4684-5134-4_28.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biotransformation
  • Bleomycin / blood*
  • DNA / blood
  • Dihydroxydihydrobenzopyrenes / metabolism*
  • Humans
  • In Vitro Techniques
  • Luminescent Measurements
  • Mutagenicity Tests
  • Mutagens / metabolism*
  • Mutagens / pharmacology
  • Mutation*
  • Neutrophils / metabolism*
  • Oxygen / blood*
  • Salmonella typhimurium / drug effects
  • Tetradecanoylphorbol Acetate / pharmacology

Substances

  • Dihydroxydihydrobenzopyrenes
  • Mutagens
  • Bleomycin
  • benzo(a)pyrene 7,8-dihydrodiol
  • DNA
  • Tetradecanoylphorbol Acetate
  • Oxygen