[Potential indications for helical tomotherapy in breast cancers]

Cancer Radiother. 2014 Jan;18(1):7-14. doi: 10.1016/j.canrad.2013.07.148. Epub 2013 Dec 5.
[Article in French]

Abstract

Purpose: To evaluate the dosimetric gain obtained in either the planning target volume or organs at risk coverage by the use of intensity-modulated radiation therapy in some particular postoperative breast cancers.

Patients and method: Prospective dosimetric comparison between monoisocentric conformal radiotherapy and intensity-modulated radiation therapy in nine patient files.

Results: Using intensity-modulated radiation therapy was shown to improve in each case, at least one conformity, homogeneity, and coverage index either for planning target volumes or for organs at risk. Intensity-modulated radiation therapy was therefore always chosen rather than conformal monoisocentric radiotherapy.

Conclusions: Indications to retain intensity-modulated radiation therapy would consist of bilateral lesions, pectus excavatum, past thoracic irradiation (Hodgkin's disease) and complex volumes in obese or overweight patients.

Keywords: Breast cancer; Cancer du sein; Intensity modulation; Modulation d’intensité; Radiotherapy; Radiothérapie.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Breast Neoplasms / complications
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / radiotherapy*
  • Carcinoma, Ductal, Breast / drug therapy
  • Carcinoma, Ductal, Breast / radiotherapy*
  • Carcinoma, Lobular / drug therapy
  • Carcinoma, Lobular / radiotherapy
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Docetaxel
  • Epirubicin / administration & dosage
  • Female
  • Fluorouracil / administration & dosage
  • Funnel Chest / complications
  • Hodgkin Disease / radiotherapy
  • Humans
  • Middle Aged
  • Neoplasms, Multiple Primary / radiotherapy
  • Neoplasms, Second Primary / radiotherapy
  • Obesity / complications
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Conformal / methods
  • Radiotherapy, Intensity-Modulated*
  • Taxoids / therapeutic use

Substances

  • Antineoplastic Agents, Phytogenic
  • Taxoids
  • Docetaxel
  • Epirubicin
  • Cyclophosphamide
  • Fluorouracil