Clinical features of West Nile virus epidemic in Dallas, Texas, 2012

Diagn Microbiol Infect Dis. 2014 Feb;78(2):132-6. doi: 10.1016/j.diagmicrobio.2013.11.006. Epub 2013 Nov 15.

Abstract

In 2012, Texas has reported the highest number of West Nile virus (WNV) cases in the United States to the Centers for Disease Control and Prevention. In this report, we conducted a retrospective chart review of 57 patients with WNV disease and analyzed the clinical features of these patients. Our results revealed that 25 (44%) patients were diagnosed with West Nile fever and 32 (56%) with West Nile neuroinvasive disease (WNND). The median age for patients with WNND was 54.5 years, and those with encephalitis were more likely to be >60 years old. Pre-existing conditions such as hypertension and diabetes were more frequent in patients with WNND. Testing both serum and cerebrospinal fluid (CSF) for antibodies diagnosed more cases of WNND than just testing serum or CSF alone. The increasing number of WNV cases during this epidemic highlights the need to increase efforts to control mosquito populations and educate the general public.

Keywords: Dallas; Epidemic; Neuroinvasive disease; WNV virus.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Female
  • Follow-Up Studies
  • Humans
  • Length of Stay
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Public Health Surveillance
  • Retrospective Studies
  • Serotyping
  • Texas / epidemiology
  • Tomography, X-Ray Computed
  • West Nile Fever / cerebrospinal fluid
  • West Nile Fever / diagnosis*
  • West Nile Fever / epidemiology*
  • West Nile virus* / classification
  • West Nile virus* / genetics
  • West Nile virus* / immunology
  • Young Adult