Anterior temporal focal abnormalities in EEG in normal aged subjects; correlations with psychopathological and CT brain scan findings

Electroencephalogr Clin Neurophysiol. 1987 Jan;66(1):1-7. doi: 10.1016/0013-4694(87)90131-3.

Abstract

Normal aged subjects (65-83 years) were examined by EEG and CT brain scan; also a Geriatric Mental Scale (GMS) and Neuropsychologic Assessment Battery were administered. Based on the EEG findings 2 subgroups could be distinguished: one with focal abnormalities in the left fronto-temporal region and one without these focal abnormalities. The focal delta subgroup proved to perform poorly on the Fluency Test, a simple quick bedside, but very sensitive, test for word association productivity. Also this subgroup showed more ventricular dilatation than the non-focal group. Therefore slight left-sided antero-temporal abnormalities in normal aged subjects are not irrelevant but an early (subclinical) sign of temporal lobe pathology as expressed in deterioration of language function.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Electroencephalography
  • Humans
  • Mental Processes / physiology*
  • Neuropsychological Tests
  • Temporal Lobe / diagnostic imaging
  • Temporal Lobe / physiology
  • Temporal Lobe / physiopathology*
  • Tomography, X-Ray Computed