First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia

Haematologica. 2013 Dec;98(12):e166-8. doi: 10.3324/haematol.2013.096750.
No abstract available

Keywords: MLL-TET1; leukemia; lineage switch.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Cell Lineage / genetics
  • DNA-Binding Proteins / genetics*
  • Fatal Outcome
  • Histone-Lysine N-Methyltransferase
  • Humans
  • Leukemia, Myelomonocytic, Acute / diagnosis
  • Leukemia, Myelomonocytic, Acute / genetics*
  • Male
  • Mixed Function Oxygenases
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Proto-Oncogene Proteins / genetics*
  • Translocation, Genetic / genetics*

Substances

  • DNA-Binding Proteins
  • KMT2A protein, human
  • Proto-Oncogene Proteins
  • Myeloid-Lymphoid Leukemia Protein
  • Mixed Function Oxygenases
  • TET1 protein, human
  • Histone-Lysine N-Methyltransferase